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KMID : 1134819980270020313
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Journal of the Korean Society of Food Science and Nutrition
1998 Volume.27 No. 2 p.313 ~ p.318
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Effect of Raw Soy Flour(yellow and black) on Serum Glucose and Lipid Concentrations in Streptozotocin - induced Diabetic Rats
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Koh Jin-Bog
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Abstract
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This study investigated the effect of raw soybean yellow(RSY) and raw soybean black(RSB) on body weights, pancreas weights, serum glucose and lipid concentrations of both normal and diabetic male rats(Sprague-Dawley, body weight 338.8±19.2g). For each experimental, some rats were injected with streptozotocin intraperitoneaI(i.p.) to induce diabets, and other rats were injected with buffer i.p. as a control group. Body weight gain(BWG) was lower in rats fed both RSY and RSB diet(3.4~5.0g BWG) than in those fed control diet(58.1g BWG). The diabetic rats showed significant decrease of body weight (-50~-67g) compared with the control rats. RSY and RSB feeding resulted in greater pancreatic weight relative to body weight, and diabetic rats fed RSY and RSB had heavier pancreatic weights relative to body weight than control rats. The levels of fasting serum glucose in diabetic rats fed both RSY and RSB decreased by 42 and 31%, respectively, compared with the diabetic control rats, but they increased by 80 and 110% compared with the normal control rats. The concentrations of total lipid, triglyceride, phospholipid and total cholesterol in serum of diabetic rats fed RSB diet were lower than those in control rats, but serum HDL-cholesterol, HDL-cholesterol/total cholesterol ratio were not affected by raw soybeans feeding. Atherogenic index was lower in diabetic rats fed RSY and RSB diet than those in control rats. The concentrations of total lipid, triglyceride and phospholipid in liver were lower in raw soybean groups or diabetic raw soybean groups than those in control group. The concentrations of cholesterol in liver of groups treated raw soybean were decreased compared with the control group.
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KEYWORD
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raw soybean, blood glucose, lipids, diabetic rats
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